Adrenoleukodystrophy (ALD) is a rare neurological disorder characterized by the accumulation of saturated very-long-chain fatty acids (VLCFAs) in the body due to mutations in the ABCD1 gene. Excess VLCFA destroys myelin, ... Read more

Peripheral neuropathy — damage to the peripheral nerves characterized by a feeling of tingling and pain in the hands and feet — is a common symptom of adrenomyeloneuropathy (AMN), the ... Read more

Caregiving is a demanding task regardless of a person’s disorder. But with rare diseases such as adrenoleukodystrophy (ALD) it can be particularly challenging, given this disease’s specific types and wide range of ... Read more

Adrenoleukodystrophy (ALD) is a rare genetic disorder caused by mutations in the ABCD1 gene located on the X-chromosome. The disease is characterized by the accumulation of excess saturated very-long-chain fatty ... Read more

Caring for someone with a rare disease such as adrenoleukodystrophy (ALD) can be very challenging. Here are some tips to help you help yourself while caring for a person with ALD. ... Read more

Adrenoleukodystrophy (ALD) is a rare, genetic disease characterized by the accumulation of saturated very long chain fatty acids (VLCFAs) that can destroy the myelin sheath and damage the adrenal glands. Symptoms of ALD — ... Read more

Adrenoleukodystrophy (ALD) is a rare disease characterized by the accumulation of saturated very-long-chain fatty acids (VLCFAs) that can destroy the myelin sheath and damage the adrenal glands, leading to symptoms that ... Read more

Lorenzo’s oil is a 4:1 mixture of two unsaturated fatty acids called oleic acid and erucic acid. Lorenzo’s oil is used as a treatment of adrenoleukodystrophy (ALD), and works by inhibiting ... Read more

Corticosteroids are medications that mimic the activity of the adrenal hormones cortisol and aldosterone, which are deficient in cases of adrenal insufficiency. These hormones are produced by the adrenal glands, ... Read more

An adrenal crisis, also known as acute adrenal insufficiency or Addisonian crisis, is potentially life-threatening event that can afflict people with a type of adrenoleukodystrophy known as Addison’s disease. These ... Read more