Posts by: Patricia Inacio PhD

Patricia Inacio PhD

Patricia holds her Ph.D. in Cell Biology from University Nova de Lisboa, and has served as an author on several research projects and fellowships, as well as major grant applications for European Agencies. She also served as a PhD student research assistant in the Laboratory of Doctor David A. Fidock, Department of Microbiology & Immunology, Columbia University, New York.

June 11, 2019June 11, 2019

Combo of Antioxidants a Potential Therapy for Adrenomyeloneuropathy, Trial Suggests

News

Targeting oxidative stress with antioxidants holds promise to improve symptoms of adrenomyeloneuropathy (AMN), a pilot Phase 2 study suggests. The results show that treatment with a combo of antioxidants decreases ... Read more

May 14, 2019May 14, 2019

#AANAM – High-dose Biotin Capsule Shows Promise in X-ALD

News

MD1003, a high-dose biotin, rescued locomotor (movement) activity and halted axon (nerve fiber) degeneration in two mouse models of X-linked adrenoleukodystrophy (ALD), including one with more severe and early disease ... Read more

March 22, 2019March 22, 2019

Blood Stem Cell Therapy MGTA-456 Showing Signs of Efficacy in Cerebral ALD, Early Trial Data Show

News

Magenta Therapeutics’ allogeneic blood stem cell therapy resolved brain inflammation and stopped the loss of white brain matter in two cerebral adrenoleukodystrophy (ALD) patients, early data from a Phase 2 clinical trial ... Read more

March 19, 2019March 19, 2019

Blood Stem Cell Transplant May Slow Cognitive Decline in Adult Cerebral ALD

News

A blood stem cell transplant may halt disease progression in certain adults with cerebral adrenoleukodystrophy (ALD), a study reports. The study, “Allogeneic hematopoietic stem cell transplantation with myeloablative conditioning for adult ... Read more

February 5, 2019February 5, 2019

Risk of Adrenal Insufficiency in ALD Is Greatest from Ages 1-10, Study Says

News

Around 80% of males diagnosed with X-linked adrenoleukodystrophy (ALD) will develop adrenal insufficiency, a retrospective study suggests. The risk, although variable with age, is higher during the first 10 years ... Read more

January 22, 2019January 25, 2019

Disease Severity, Transplant Source Influence Long-term Success in Childhood Cerebral X-ALD

Just Published, News

The success of blood stem cell transplants in boys with childhood cerebral X-linked adrenoleukodystrophy (CCALD) is influenced by the severity of white matter loss in the brain and the stem ... Read more

January 3, 2019January 4, 2019

Data Point to Promise of Stem Cell Therapies for CALD Patients, Bluebird Bio Reports

News

Bluebird Bio presented recent data from clinical trials in which two of its lead investigational therapies for cerebral adrenoleukodystrophy (CALD) were tested — a gene therapy that uses patient-derived stem ... Read more